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Identification of Arp2/3 Complex Subunits as Prognostic Biomarkers for Hepatocellular Carcinoma.
Huang S, Li D, Zhuang L, Sun L, Wu J. Huang S, et al. Front Mol Biosci. 2021 Jul 9;8:690151. doi: 10.3389/fmolb.2021.690151. eCollection 2021. Front Mol Biosci. 2021. PMID: 34307456 Free PMC article.
The results revealed that mRNA expression of Arp2/3 members (ACTR2, ACTR3, ARPC1A, APRC1B, ARPC2, ARPC3, ARPC4, ARPC5, and ARPC5L) was upregulated in HCC. ...The GSEA results indicated that ACTR3, ARPC2, and ARPC5 are involved in multiple cancer-related pathw …
The results revealed that mRNA expression of Arp2/3 members (ACTR2, ACTR3, ARPC1A, APRC1B, ARPC2, ARPC3, ARPC4, ARPC5, and ARP …
Identification of Key Genes for Hepatitis Delta Virus-Related Hepatocellular Carcinoma by Bioinformatics Analysis.
Zhang C, Wu S, Yang XD, Xu H, Ma T, Zhu QX. Zhang C, et al. Turk J Gastroenterol. 2021 Feb;32(2):169-177. doi: 10.5152/tjg.2020.191003. Turk J Gastroenterol. 2021. PMID: 33960941 Free PMC article.
RESULTS: A total of 93 commonly upregulated genes and 36 commonly downregulated genes were found. The top 5 upregulated hub genes were TFRC, ACTR2, ARPC1A, ARPC3, and ARPC2. The top 5 downregulated hub genes were CTNNB1, CCND1, CDKN1B, CDK4, and CDKN1A. In the valid …
RESULTS: A total of 93 commonly upregulated genes and 36 commonly downregulated genes were found. The top 5 upregulated hub genes were TFRC, …
[Construction and expression of the fusion vector of His-tagged human ARPC2 gene].
Gong XW, Peng Y, Liu JH, Li ZJ, Deng P, Qin QH, Jiang Y. Gong XW, et al. Di Yi Jun Yi Da Xue Xue Bao. 2004 Jun;24(6):628-30, 635. Di Yi Jun Yi Da Xue Xue Bao. 2004. PMID: 15201074 Chinese.
OBJECTIVE: To construct the expression vector of His-ARPC2 fusion protein and obtain its expression and purification in E. coli. ...RESULTS: The constructed His-ARPC2 fusion protein vector was highly efficiently expressed in E. coli. ...
OBJECTIVE: To construct the expression vector of His-ARPC2 fusion protein and obtain its expression and purification in E. coli. ...R …
Protein Interaction Network of Human Protein Kinase D2 Revealed by Chemical Cross-Linking/Mass Spectrometry.
Häupl B, Ihling CH, Sinz A. Häupl B, et al. J Proteome Res. 2016 Oct 7;15(10):3686-3699. doi: 10.1021/acs.jproteome.6b00513. Epub 2016 Sep 2. J Proteome Res. 2016. PMID: 27559607
Remarkably, the entire seven-subunit Arp2/3 complex (ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, ACTR3, ACTR2) as well as ARPC1A and ARPC5L, which are putative substitutes of ARPC1B and ARPC5, were identified. ...
Remarkably, the entire seven-subunit Arp2/3 complex (ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, ACTR3, ACTR2) as well as ARPC1A and A …
Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome trafficking.
Zhang Y, Shen H, Liu H, Feng H, Liu Y, Zhu X, Liu X. Zhang Y, et al. Sci Rep. 2017 Aug 21;7(1):8952. doi: 10.1038/s41598-017-08357-4. Sci Rep. 2017. PMID: 28827576 Free PMC article.
However, how surface TCR levels are regulated and its biological significance on T cells remains largely unknown. Here, we show that the T cell-specific deletion of Arpc2, a component of Arp2/3 complex, results in compromised peripheral T cell homeostasis. Arp2/3 complex-n …
However, how surface TCR levels are regulated and its biological significance on T cells remains largely unknown. Here, we show that the T c …